Biotin repressor stress

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August undefined, 2024

Web2 days ago · We found that the expression of genes related to a lytic phage lifestyle in the phage-plasmid were highly up-regulated after the observation of mutations in the repressor sequence, such as the... WebDec 25, 1982 · A bifunctional protein. Definitive evidence is presented for the bifunctional …

Antihypertensive effect of biotin in stroke-prone spontaneously ...

WebFind patient medical information for Stress Formula/Iron/Biotin oral on WebMD … WebFeb 1, 2003 · The biotin repressor is an allosterically regulated, site-specific DNA-binding protein. Binding of the small ligand bio-5'-AMP activates repressor dimerization, which is a prerequisite to DNA binding. porsche 934.5 super top speed

Co-repressor Induced Order and Biotin Repressor

WebConsist- ent with the presence of the biotin repressor BirA, ... Genomic organization of genes involved in oxidative stress response Figure 9 Genomic organization of genes involved in oxidative ... WebNov 15, 2013 · Many biological switches including the stress response [1] and biofilm formation [2] in bacteria and inflammation [3] and development [4] in higher organisms are controlled at the level of protein:protein interactions. In each of these systems, the switch involves swapping of one protein interaction partner for another. WebOct 1, 1992 · The three-dimensional structure of BirA, the repressor of the Escherichia … sharp shooting pain in leg

Disordered to ordered folding in the regulation of diphtheria toxin ...

The Biotin Repressor: Thermodynamic Coupling of …

WebSep 25, 2001 · Diphtheria toxin repressor protein (DtxR) is a 226-amino acid residue, iron-dependent transcriptional regulator of genes in Corynebacterium diphtheriae that code for diphtheria toxin and proteins involved in iron uptake and oxidative stress (1, 2).DtxR is the best characterized member of a family of related proteins from primarily Gram-positive … WebMar 5, 2024 · Biotin biology in E. coli and S. aureus.a BirA is a multi-functional protein … sharp shooting pain in thumbWebMay 24, 2016 · The paradigm version of BPL is the Escherichia coli BirA that is also a repressor for the biotin biosynthesis pathway. Streptococcus suis, a leading bacterial agent for swine diseases, seems to... sharp shooting pain in wrist and hand

"WebSep 11, 2014 · Small ligand, bio-5'-AMP, binding and dimerization of the Escherichia coli biotin repressor are allosterically coupled ... Macromolecules Find similar proteins by: (by identity cutoff) 3D Structure Small Molecules Experimental Data & Validation Experimental Data Method: X-RAY DIFFRACTION Resolution: 2.31 Å R-Value Free: 0.218 R-Value … " - Biotin repressor stress

Biotin repressor stress

Functional definition of BirA suggests a biotin …

WebJul 13, 2024 · Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER associated stress proteins are molecular chaperones essential for cellular homeostasis. The major functions of ... WebNov 9, 2002 · The Escherichia coli biotin repressor, an allosteric transcriptional …

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WebJan 31, 2003 · The biotin repressor is an allosterically regulated, site-specific DNA-binding protein. Binding of the small ligand bio-5′-AMP activates repressor dimerization, which is a prerequisite to DNA binding. Multiple disorder-to-order transitions, some of which are known to be important for the functional allosteric response, occur in the vicinity ... WebThe identity of the biotin repressor and the biotin-apo- BCCP ligase of E. coli was strongly indicated by the very detailed genetic studies of Barker and Campbell (3, 4) who showed that lesions in the same genetic entity, the birA gene, gave rise to both biotin-apoBCCP ligase deficiency and to depression of the biotin operon.

WebFeb 2, 2005 · The Escherichia coli biotin repressor is an allosteric DNA binding protein and is activated by the small molecule bio-5‘-AMP. Binding of this small molecule promotes transcription repression complex assembly between the repressor and the biotin operator of the biotin biosynthetic operon. WebNov 12, 2024 · OsClo5 functions as a transcriptional co-repressor by interacting with OsDi19-5 to negatively affect salt stress tolerance in rice seedlings. Pei Jing, ... The MBP-OsDi19-5 was incubated with the biotin-labeled wild-type Di19-binding sequence (DIBS) probe or mutated DIBS probe, and the non-labeled DIBS probe was used as a competitor ...

WebWe also demonstrate that the S. aureus BirA protein is a transcriptional repressor of … WebSep 24, 1999 · The Escherichia coli repressor of biotin biosynthesis (BirA) is an allosteric site-specific DNA-binding protein. BirA catalyzes synthesis of biotinyl-5′-AMP from substrates biotin and ATP and the adenylate serves as the positive allosteric effector in binding of the repressor to the biotin operator sequence.

WebFeb 13, 1996 · The Escherichia coli repressor of biotin biosynthesis (BirA) is an allosteric site-specific DNA binding protein. The protein is composed of three structural domains. Contact with the biotin operator (bioO) in the transcriptional repression complex is made by the N-terminal domain which contains a helix−turn−helix structural module. The …

WebNov 14, 2024 · Acid stress reduces the internal pH below this threshold, increasing OmpR dimerization and DNA binding. ... in the ompR null mutant, suggesting that E. coli OmpR also functions as a repressor at ... sharp shooting pain in shin boneWebNov 14, 2024 · In this study, we establish OmpR as a global regulator of acid and osmotic stress in S. Typhimurium and E. coli. OmpR represses distinct sets of genes based on the intracellular pH threshold... sharp shooting pain in eye socketWebMay 15, 1998 · The Escherichia coli repressor of biotin biosynthesis, BirA, binds to a 40 bp operator site (bioO) to repress transcriptional initiation at the two divergent promoters of the biotin biosynthetic operon (Figure 1A; Otsuka & Abelson, 1978). porsche 935 street priceWebMar 5, 2024 · BirA is a transcriptional repressor of the biotin biosynthesis operon ( bioO, shaded gray) in both bacteria. BirA is proposed to also regulate expression of the biotin transport protein BioY and the yhfS - yhfT operon in S. aureus. b Sequences of the promoters for bioO in E. coli and bioO, bioY, and yhfS-yhfT in S. aureus are shown. porsche 944 alpine whiteWebJan 1, 2001 · Cooperative association of the Escherichia coli biotin repressor with the biotin operator is allosterically activated by binding of the corepressor, bio-5'-AMP. The corepressor function of... porsche 944 beamngWebEnzymatic Biotinylation: BirA. Ligation of biotin to a protein is a specific post-translational … porsche 935/78 moby dickWebMar 24, 2006 · BirA is a bifunctional enzyme that adenylates biotin and then uses the … sharp shooting pain in neck