WebJul 23, 2014 · Pompe disease is a lysosomal storage disorder in which acid alpha-glucosidase (GAA) is deficient or absent. Deficiency of this lysosomal enzyme results in progressive expansion of glycogen-filled lysosomes in multiple tissues, with cardiac and skeletal muscle being the most severely affected. The clinical spectrum ranges from fatal … WebThe cytoplasmic inclusions are dead, non-functional and unimportant for fungal survival for example stored food (glycogen and oil drops), pigments and the secretory granules. The cell organelles are endoplasmic reticulum, mitochondria, ribosomes, golgi bodies and vacuoles (Fig. 4.37A).
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WebLESTER D.R. THOMPSON, in Modern Surgical Pathology (Second Edition), 2009 Special Studies PAS-positive, diastase-sensitive cytoplasmic granules of glycogen can be demonstrated, and rod-shaped crystals (“jackstraws”) can be seen in the cytoplasm of some cells (adult type). WebThe following points highlight the eight important cytoplasmic inclusions found in bacteria. The cytoplasmic inclusions are: 1. Ribosomes 2. Polyphosphates 3. Poly-β … notion of face
Liver, Hepatocyte - Glycogen Accumulation and Depletion
WebA periodic acid–Schiff stain of the marrow aspirate may highlight globular or coarsely punctate positive reactivity in erythroblasts with cytoplasmic vacuoles (see Fig. 18.4E ). An iron stain of the marrow aspirate smear is necessary to look for ring sideroblasts (see Fig. 18.4D ). Regarding the granulocytes, a combined butyrate esterase and ... WebMar 22, 2024 · Glycogen-rich clear cell carcinoma of the breast is an extremely rare subtype of invasive breast carcinoma, accounting for up to 3% of all breast carcinomas. The tumor is composed of polygonal cells with abundant clear cytoplasm containing glycogen and has a very controversial prognosis. WebAntibody-mediated enzyme replacement therapy targeting both lysosomal and cytoplasmic glycogen in Pompe disease. Pompe disease is characterized by accumulation of both lysosomal and cytoplasmic glycogen primarily in skeletal and cardiac muscles. how to share my kindle vella story