WebHere, we investigated the utility of a new enzymatic bioconjugation method, called lysine acylation using conjugating enzymes (LACE), to chemoenzymatically modify protein cages. We equipped two structurally distinct protein capsules with a LACE-reactive peptide tag and demonstrated their modification with diverse ligands. WebCovalent inhibitors are widely used in drug discovery and chemical biology. Although covalent inhibitors are frequently designed to react with noncatalytic cysteines, many …
DOI:10.1002/cbic.200600191 …
Web12 apr. 2024 · In this brief review, the small molecular fluorescent probes employed in fatty liver are summarized, mainly focusing on the last four years. ... Shin, I.; Yoon, J. Fluorescent and luminescent probes for detection of reactive oxygen and nitrogen species. Chem. Soc. Rev. 2011, 40, 4783–4804. [Google Scholar] Terai, T.; Nagano, T. … Web31 iul. 2024 · a, General protocol for lysine reactivity profiling by isoTOP-ABPP.Cellular lysates are labelled with an amine-reactive STP alkyne probe (1) at different … greenburg dentistry ocala fl
Recent advances in the development of activatable multifunctional ...
WebMolecular Probes manufactures a wide variety of amine-reactive fluorescent dyes, biotins, and other ... as the pK a of the terminal amine is lower than that of the lysine ε-amino ... Web8 mai 2008 · A new fluorescent probe, N-benzoyl rhodamine B–hydrazide, for the hypochlorite anion has been designed and synthesized.The probe displays a highly selective fluorescence-on response to OCl − only, and not to any of the other ions and oxidants that were examined (see scheme). This remarkable property gives the probe … Web8 dec. 2024 · Not until 2012 did Han’s group report the construction of cyanine-based fluorescent probes 1 and 2 for the selective recognition of HOBr , which is the first example of a fluorescent probe for HOBr . In this system, the cyanine platform served as a signaling fluorophore, while the 4-hydroxylamino-2,2,6,6-tetramethylpiperidine-N-oxyl (TemOH ... green burberry sunglasses