WebBisphosphonates Accession Number DBCAT001016 Description Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. WebRussell RG, Watts NB, Ebetino FH, Rogers MJ: Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int. 2008 Jun;19(6):733-59. doi: 10.1007/s00198-007-0540-8. Cremers S, Drake MT, Ebetino FH, Bilezikian JP, Russell RGG: Pharmacology of bisphosphonates.
Bisphosphonates Side-effects, uses, time to work - Versus Arthritis
WebAntiresorptive drugs (e.g. bisphosphonates, oestrogen, denosumab) reduce bone turnover by distinct mechanisms. Denosumab, a recently approved therapy, is a fully human monoclonal antibody that binds the cytokine RANKL (receptor activator of NFκB ligand), an essential factor initiating bone turnover. Web1 apr. 2011 · Bisphosphonates are currently the most widely used antiresorptive therapies. They act by binding the mineral c … To treat systemic bone loss as in osteoporosis … quotes about making commitments
Understanding bisphosphonates and osteonecrosis of the jaw …
WebZoledronic acid is a bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors. Brand Names Aclasta, Reclast, Zometa Generic Name Zoledronic acid DrugBank Accession Number … Web17 jan. 2024 · Teriparatide is a medication used in the management and treatment of osteoporosis. It is in the anabolic class of osteoporosis medications. This activity reviews the indications, actions, and contraindications for teriparatide as a valuable agent in managing osteoporosis. This activity will highlight the mechanism of action, adverse event profile, … WebBisphosphonate mechanism of action. The nitrogen-containing bisphosphonates (N-BPs), alendronate and risedronate, are the only pharmacologic agents shown to prevent … quotes about making errors